Precision Oncology and Cancer Immunotherapy

At Andremacon, we are committed to pioneering advancements in precision oncology and cancer immunotherapy. By harnessing genomic profiling and molecular diagnostics, we map the specific genetic and molecular signatures of each tumor, allowing us to develop individualized therapies that target unique cancer vulnerabilities. This approach aims to maximize therapeutic efficacy while minimizing adverse effects, embodying the potential of personalized medicine in oncology.

Targeted Therapies: Addressing Resistance at the Cellular Level

Our research focuses on the mechanisms of cancer stem cells and drug-resistant tumor cells, which are critical drivers of tumor progression, metastasis, and therapy resistance. Andremacon’s team is developing an array of specific inhibitors - including advanced antibodies, nanobodies, and small molecules -  that disrupt resistance pathways. These inhibitors are designed to selectively target malignant cells while sparing healthy tissues, ultimately reducing the likelihood of recurrence and enhancing treatment effectiveness.


Immunotherapy: Leveraging the Immune System’s Cancer-Fighting Potential


In addition to targeted therapies, we are at the forefront of innovative immunotherapies that harness the immune system to recognize and eradicate cancer cells. By advancing immune checkpoint inhibitors and adoptive cell therapies, we’re developing a suite of compounds and technologies that strengthen the immune system’s capacity to penetrate and counteract solid tumors. This research includes novel immunostimulant compounds that address tumor immune evasion, providing robust defenses against cancer cell proliferation.


Combination Therapies: Enhancing Efficacy Through Multi-Modal Approaches


Acknowledging the inherent complexity and heterogeneity of cancer, we are actively exploring combination therapies that integrate targeted treatments with immunotherapeutic modalities. By combining different therapeutic approaches, we aim to overcome resistance mechanisms, optimize therapeutic response, and improve overall patient outcomes.

Our commitment to advancing cell-based therapies includes the development of CAR-T cells, natural killer (NK) cells, and CAR-M therapies to improve cell penetration and immune activity in solid tumors. Andremacon’s high-throughput technologies and co-stimulating antibodies are positioned to expand the reach of both autologous and allogeneic cell therapies, providing broader access and efficacy for patients. Our innovations also anticipate the application of cell-based therapies to treat a range of conditions, including autoimmune and infectious diseases.